What is Sildenafil Citrate 100mg?
Sildenafil citrate 100mg fits into the pharmacological category of drugs known as phosphodiesterase 5(PDE5) inhibitors. PDE5 enzymes regulate the production of cyclic Guanosine Monophosphate (cGMP) enzyme. An adequate level of cGMP and PDE5 enzyme is necessary for proper erections during intercourse. In a person suffering from erectile dysfunction, there are abnormally high levels of PDE5 enzymes. These high levels of PDE5 result in more degradation of the cGMP enzyme. cGMP enzyme is an enzyme responsible for flow in the penile regions.
With more degradation of the cGMP enzyme, not enough blood flows into the organ. This causes erectile dysfunction in men. The whole idea behind PDE5 inhibitor medication is to control the excess production of PDE5 enzymes and control excess degradation of cGMP enzyme.
The medication is primarily used to achieve optimized productions of cGMP and PDE5 enzymes. The main concept behind these medications is to allow an adequate amount of blood flow into the organ and to allow blood flow in a regulated manner out of the organ during intercourse. Sildenafil Citrate 100mg works within a period of 40 minutes to 1 hour after its intake and the impact persists for around 4 to 6 hours. After consuming Sildenafil Citrate 100mg, a man is able to achieve proper penile erections and are able to overcome impotence during sexual acts.
What is the action mechanism of Sildenafil Citrate?
Soon after consuming this medication, the active ingredient starts inhibiting the production of enzymes, particularly known as phosphodiesterase 5 (PDE 5). PDE5 is the main cause of the constrained blood flow toward the penile area that leads to erectile dysfunction.
After confining the enzyme’s activity, sildenafil citrate increases the production of biochemical nitric oxide(NO) and an enzyme is known as guanylyl cyclase. Higher guanylyl cyclase levels sequentially increase the making of a strong vasodilator inside the human body known as cyclic Guanosine Monophosphate (cGMP).
The cGMP smoothens muscles of the penile area, widens the blood vessels in the penile region and then results in improved blood flow. This entire process of PDE5 enzyme inhibition, adequate cGMP enzyme production, the extra blood supply to the penile region and the expansion of blood vessels with the help of nitric acid results in a strong erection of the penile organ in men suffering from ED. Sildenafil Citrate 100mg tablets are very effective for treating erectile dysfunction. Men like to buy sildenafil citrate 100mg online as it is available at low prices online.
Things to Remember:-
Sildenafil citrate works effectively in most men. Like all other medications, there are certain things that one should remember before using Sildenafil Citrate pills:-
- The consumption of alcohol simultaneously can reduce the effectiveness of this medication. Alcohol affects the potential of this drug. In some patients, it can cause serious side effects too.
- Patients above 65 years of age may experience some delay as a result of Sildenafil Citrate.
- Fat-rich and Heavy meals should be avoided before consuming Sildenafil Citrate pills. The absorption rate of this medication falls in people who have consumed heavy means prior to consuming this tablet. This affects the potential of this medication.
- Medications such as rifampicin (utilized for curing tuberculosis) can alter blood pressure levels to serious levels; if taken along with this medication.
- Store the Sildenafil Citrate tablet in a cool and dry place. The best way is to keep these medications in air-tight containers in an isolated manner.
- Women and children should not use this medication.
- People having a history of heart, liver, and kidney disease should only consume this medication after consulting their physician.
- Diabetic patients should only use sildenafil citrate after having a prescription from a certified physician.
What is the right dosage of Sildenafil citrate?
- The pills of Sildenafil citrate are accessible in 25 mg, 50 mg, as well as 100 mg doses. Out of all most men prefer to buy Sildenafil Citrate 100mg online to treat regular erectile dysfunction issues.
- The pill is to be swallowed uncut with a glass of water.
- You are not allowed to chew, crush, or break the tablet at the time of consumption.
- A gap of 24 hours in the middle of 2 dosages must be kept to evade unwanted consequences.
At the beginning of treatment, a physician examines the health of a patient. After assessing the intensity of erectile dysfunction, a 25 mg pill of Sildenafil Citrate is prescribed. The dose can be later adjusted after assessing the patient’s response to the medication. Mostly, Patients have been prescribed Sildenafil Citrate 100mg as it is the effective dose to treat erectile dysfunction.
NOTE: A person must remember that medications comprising nitrates or the same ingredient (that are utilized for the cure of chest or angina) and recreational medications known as poppers must not be consumed with Sildenafil Citrate tablets.. The combination of such drugs can result in a severe drop in blood pressure.
Explain to your doctor if you have any kind of medical history such as:
- Blood sicknesses such as multiple myeloma, sickle cell anaemia, or leukaemia
- Cardiac ailments such as Ischemic heart disease, high blood pressure, pericardial disease, cardiomyopathy, Coronary artery disease, and valvular, heart disease, congestive heart failure or heart attack.
- Liver or kidney disease or failure.
- Bleeding disorders such as haemophilia
- Retinitis pigmentosa (a hereditary ailment of the eye)
- Penile abnormalities (such as Peyronie’s disease)
- Abdominal ulcers
Things to Remember!
Use with Food: The pill of Sildenafil citrate should be consumed with a light diet or on an empty stomach.
Alterations of dosages in Particular Circumstances: The pill should not be consumed with nitrates or its supporters. The primary dosage of 25 mg must be consumed only once a day if it is prescribed with the alpha-blocker tablets.
Alterations of dosages in Exceptional Populations: In men having the age more than 60 years, people with severe renal damage (creatinine clearance <30 mL/minute), and people with hepatic injury (for example, cirrhosis), a decreased dosage might be recommended by the physician. Mostly a 25 mg Sildenafil Citrate pills are prescribed in this circumstance.
What happens in case of missing the dose?
For treating erectile dysfunction, the dosage of sildenafil citrate should be taken as necessary. There are fewer chances that a person might miss the prescribed amount. For treating PAH(Pulmonary Arterial Hypertension), a 25 mg sildenafil citrate may be prescribed on regular basis. In such cases, if a dose is missed, it is best to consume it as soon as a patient becomes aware. In case a patient becomes aware of the missed dose at a time that is near the next scheduled dose, it is best to wait can consume only the scheduled dose. A patient, at any stage, should not take a double dose.
What happens in case of a pill overdose?
The symptoms of overdosing result in prolonged erections known as “Priapism” along with chest pains, nausea, and irregular heartbeat. You should seek advice straight from your doctor in case of an overdose.
What are the side effects of sildenafil citrate 100mg tablets?
What are the side effects of Sildenafil citrate?
The side effects of Sildenafil citrate generally subside once the patient’s body gets used to it. If the consequences continue then, medical aid is required instantly. Below are a few common side effects of Sildenafil citrate:
- Giddiness and Dizziness
- Nasal congestion
- Blurred vision
- Facial Flushing
- Chest pain
- Prolonged erection
What are the warnings given along with the sildenafil citrate?
- Sildenafil Citrate should not be used by patients having a history of priapism.
- The pill is not suggested for heart patients. Patient’s having heart issues should only consume this medication on approval of the doctor.
- The effect of unexpected vision loss arising in single or both eyes might be an indication of NAION (non-arteritis anterior ischemic optic neuropathy). It requires therapeutic help straightaway. Patients suffering from NAION should use this medication only after prescription.
- The pills of sildenafil citrate are not meant for recreational usage and should be used with utmost care.
- Quick medical assistance might be needed in case of a sudden loss of hearing.
- Regular usage of sildenafil citrate can cause a sense of dependency. Therefore, Sildenafil Citrate should only be used if required.
- Use of Sildenafil Citrate in women and children is strictly prohibited.
Questions customers ask before they buy Sildenafil Citrate 100mg Online!
How much time do the effects of sildenafil citrate last?
The effect of Sildenafil citrate inside the human body depends on numerous parameters and may vary. However, the average duration for which the action of the pill lasts is 5 hours. The effect of the pill begins to subside 4 hours after the consumption of the first dosage.
Is it possible to buy Sildenafil citrate pills online?
Yes, one can buy Sildenafil Citrate online at Allmedcare.com with free doorstep delivery. The pills are available at a very low price along with rebates and discounts and that too without compromising the quality.
What is the difference between Viagra® vs. “Sildenafil citrate”?
Sildenafil citrate is an active ingredient that is founded in all generic tablets and Viagra®. The resemblance between sildenafil citrate and the branded Viagra is that the former is the active ingredient while the latter is the name of the branded drug. The generic form of Sildenafil citrate works in the same way as the brand medicine. The only difference between the two is the price.
One can buy Sildenafil Citrate 100mg online at a much cheaper price than the brand Viagra. Both these medications treat erectile dysfunction effectively.
Should I have to consult the doctor before increasing the Dosage of the Drug?
Sildenafil Citrate 100mg is a medication available on prescription. The dosage should always be managed by health experts. Therefore, it is mandatory and equally important to consult a physician. Higher dosages of the drug can lead to fatal health results.
Can I use Sildenafil Citrate with other Drugs meant for Blood Pressure and heart-related disorders?
No. You should first consult your physician before taking the drug if you are diabetic, have a heart problem, abnormal blood pressure, kidney disorders, or any other disease.
Can I take Sildenafil Citrate on empty stomach?
Yes, You can. Sildenafil Citrate 100mg is the prescribed ED(erectile dysfunction) drug and you can take it on empty stomach. It is a pretty safe tablet.
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